Bioprocess bag management system
Bag Management system
Bag Management system
Supporting the usage and handling of flexible containers for bulk intermediate reagents and solutions, the Nalgene Bioprocess Bag Management system provides an organised and systematic means of managing flexible bags. A rigid, puncture-resistant polycarbonate shell top and bottom forms a protective barrier around the bioprocess bag. This novel management system isolates and stabilises the bag and tubing during transport, effectively addressing the rapidly expanding demand for single-use flexible systems in biotechnology and biopharmaceutical applications.
The system facilitates easy handling and ensures integrity is maintained by minimising bag and port movement during transportation. A front compartment provides useful storage for tubing and the interior is contoured to fit commercially available bags such as the Thermo Scientific Hyclone 5L and 20L Labtainer Bioprocess containers. Users can choose between a clear version for easy sample viewing and an opaque version to protect light-sensitive contents. With the ability to withstand temperatures from -80 to 121oC, these systems are suitable for frozen and autoclave applications. When assembled, units are stackable to save space, and when not in use, the shells are nestable and easy to store.
Platform for increased sensitivity of in vitro toxicity testing
In vitro toxicity testing
Thermo Fisher Scientific
The Cellomics ToxInsight solution offers a unique combination of imaging hardware and analysis software, and couples pre-validated panels of toxicity assessment targets, to provide a robust risk assessment tool for in vitro toxicity testing. Traditional methods of assessing toxicity in vitro measure single targets and have a record of low predictive power. Recent published research has shown that cellular imaging, which combines multiple toxicity targets in single cells, provides a better indicator of compound toxicity. Such rich profiles of cellular toxicity have the potential to revolutionise the way toxicity testing is performed, from reducing late stage drug failures due to adverse toxicity (hence lowering overall drug development costs), to better understanding of the effect of environmental toxins as well as ensuring the products we use from shampoos to topical skin treatments are safe.
Harnessing the power of cell imaging to make multiple toxicity assessments on a cell by cell basis, the ToxInsight IVT platform unites automated instrumentation, software, and reagent ‘cartridges’ within a simple, intuitive workflow, offering improved sensitivity and specificity compared to traditional methods.