- Plexxikon Announces PLX4032 Phase 1 Data Showing Objective Responses in Metastatic Melanoma Patients
–-Personalized Medicine for Deadliest Form of Skin Cancer--
Plexxikon Inc. has announced preliminary data from a Phase 1 clinical study investigating PLX4032 (R7204). PLX4032 is a novel, oral and highly selective drug that...
(Issue date: 09 June 2009)
- Hydrogen peroxide marshals immune system
When you were a kid your mom poured it on your scraped finger to stave off infection. When you got older you might have even used it to bleach your hair. Now there’s another possible function for this over-the-counter colourless...
(Issue date: 09 June 2009)
- Research identifies 3D structure of key nuclear pore building block
The genome of complex organisms is stashed away inside each cell’s nucleus, a little like a sovereign shielded from the threatening world outside. The genome cannot govern from its protective chamber, however, without knowing...
(Issue date: 09 June 2009)
- How Plants Make Eggs
A long-standing mystery surrounding a fundamental process in plant biology has been solved by a team of scientists at the University of California, Davis. The group’s groundbreaking discovery that a plant hormone called auxin is...
(Issue date: 09 June 2009)
- New Lead for Autoimmune Disease
A drug derived from the hydrangea root, used for centuries in traditional Chinese medicine, shows promise in treating autoimmune disorders, report researchers from the Program in Cellular and Molecular Medicine and the Immune...
(Issue date: 09 June 2009)
- Liver disease "shrunk" by blood-pressure drug
A blood-pressure medicine has been shown to reverse the effects of early-stage liver failure in some patients. Newcastle University researchers analysed a small clinical trial of losartan, a drug normally prescribed for...
(Issue date: 02 June 2009)
- CSHL scientists discover specific small RNA pathways protecting the germ line from genetic parasites
Cells of higher organisms are in a constant struggle against some of their own DNA – repeated bits of DNA sequence called transposons that have infiltrated host genomes over the eons. Transposons damage the rest of the genome...
(Issue date: 02 June 2009)
- Benefit of aspirin for healthy people is uncertain
Researchers say the benefits of taking asprin don't outweigh the risks. A new study has shown that, while taking aspirin is beneficial in preventing heart attacks and strokes among people with established cardiovascular disease...
(Issue date: 02 June 2009)
- Salk Scientist Inder Verma to Receive 2009 Outstanding Achievement Award from American Society of Gene Therapy
Salk Professor Inder M. Verma, Ph.D., one of the world's leading authorities on the development and use of engineered viruses for gene therapy, has been named the 2009 recipient of the American Society of Gene Therapy's...
(Issue date: 02 June 2009)
- Slicing chromosomes leads to new insights into cell division
By using ultrafast laser pulses to slice off pieces of chromosomes and observe how the chromosomes behave, biomedical engineers at the University of Michigan have gained pivotal insights into mitosis, the process of cell...
(Issue date: 02 June 2009)
- Sugarcoating fruit fly development
Proteins are the executive agents that carry out all processes in a cell. Their activity is controlled and modified with the help of small chemical tags that can be dynamically added to and removed from the protein. 25 years...
(Issue date: 02 June 2009)
- What blinking molecules reveal about cell structure
There has been a strong drive behind the development of high-resolution microscopic methods in recent years. Developers are aiming at achieving a high spatial resolution right down to the nano scale for making clear, precise...
(Issue date: 28 May 2009)
- Some neural tube defects in mice linked to enzyme deficiency
Women of childbearing age can reduce the risk of having a child born with a neural tube defect such as spina bifida by eating enough folate or folic acid. However, folate prevents only about 70 percent of these defects. New...
(Issue date: 28 May 2009)
- Full mouse genome reveals treasury of new genes
Researchers have sequenced the full mouse genome for the first time. The mouse has become only the second mammal after the human to have its entire genome laid bare, and University of Oxford researchers playing a key role....
(Issue date: 28 May 2009)
- Researchers gain ground in efforts to fight parasite infection
New findings by researchers UT Southwestern Medical Center are accelerating efforts to eradicate worm infections that afflict a third of the world’s population. The new findings demonstrate that a biochemical system that controls...
(Issue date: 28 May 2009)
- ISU researcher identifies genetic pathway responsible for much of plant growth
Researchers at Iowa State University have discovered a previously unknown pathway in plant cells that regulates plant growth. Yanhai Yin, an assistant professor in genetics, development and cell biology, examined signalling...
(Issue date: 28 May 2009)
- Novel Vaccine Approach Offers Hope in Fight Against HIV
A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. By using gene transfer...
(Issue date: 28 May 2009)
- Human nose too cold for bird flu, says new study
Avian influenza viruses do not thrive in humans because the temperature inside a person's nose is too low, according to research. The authors of the study, from Imperial College London and the University of North Carolina, say...
(Issue date: 18 May 2009)
- Equality of the sexes? Not always when it comes to biology
MUHC researchers demonstrate that oestrogen renders the innate immune system of women more powerful than that of men. When it comes to immunity, men may not have been dealt an equal hand. The latest study by Dr. Maya Saleh, of...
(Issue date: 18 May 2009)
- Using high-precision laser tweezers to juggle cells
Researchers at the University of Gothenburg, Sweden, have developed a new method to study single cells while exposing them to controlled environmental changes. The unique method, where a set of laser tweezers move the cell around...
(Issue date: 18 May 2009)
